Celastrus Paniculatus : Is It An Effective Nootropic Ingredient?


Celastrus Paniculatus : Is It An Effective Nootropic Ingredient?


I love discovering new nootropic ingredients and one that I only recently stumbled across is a plant extract called Celastrus Paniculatus.

Thought to have some great cognitive boosting effects, but whats the real story here? Does it really work? What does science say about it?

This article takes a good look at Celastrus Paniculatus, and finds out the facts surrounding its claimed nootropic benefits..

Celastrus Paniculatus is a woody, wild plant that is native to parts of India, more commonly it is referred to as:

  • Black Oil Plant
  • Climbing Staff Tree
  • Intellect Tree

A deciduous vine it can grow quite large with stems measuring some 10cm in diameter and up to 6 meters long. It has a pale brown rough looking bark, and has simple oval leaves.  The fruit are a yellow colour, they contain the seeds that are used in supplements..

The extract is taken from the seeds and is used in traditional ayurvedic medicines. There are two main uses, it is thought that it can help boost cognition, the in oil form (extracted from the seeds, it is believed to calm skin inflammation. It also has reported intestinal health benefits.

The actual science behind this extract is not fully understood as of yet, and as for a recommended daily dose, there appears to be no solid recommendations currently.

That said there are a few nootropic companies that are now starting to include it in their formulas. Lets take a more in-depth look into Celastrus Paniculatus. 

Find out what we DO KNOW.

celastrus Seeds

1, It Can Boost Cognitive Health : 

There are some animal studies that demonstrate that it might be able to help restore working memory and also help reduce the effects of stress on the brain. 

Sure these initial studies were carried out on Wistar rats but with so many similarities between them and us, the results are likely to be replicated in humans.

2, It Can Help Reduce Inflammation

It is thought, certainly in initial animal studies that it can help replicate the pain relieving effects of aspirin. Scientist also suggest that can help soothe inflammation too

There is a lack of human studies thats for sure, but animal studies do give a pretty good indication of its potential effects

3, Balances Neurotransmitters In the Brain

Another claimed benefit of Celastrus is its effects can include the balancing of key neurotransmitters such as serotonin, dopamine and noradrenaline. This boosted overall learning ability and also memory.

4, Helps Boost Exercise And Recovery

When given the seeds as a daily supplement, mice and rats were able to extend periods of intense activity, without causing harm to their muscles or in fact their DNA. 

This means that in humans, it could help them to exercise for longer, helping to boost both cognitive and physical functions.

5, Supports Heart Health

celastrus paniculatus

There are signs ( again in animal studies) that daily supplementing with Celastrus could help protect the heart from disease

6, Your Gut

As above, studies (on both animals AND Humans this time )have demonstrated that the seeds can help boost the health of our gut.

7, Cancer

One of the most exciting things about Celastrus that I discovered is that there is potential for it to be used as an anti cancer treatment. (in particular Breast Cancer)

It has shown some anti tumour effects, not only that I discovered that one of the compounds in the extract actually helped to induce the death of cancer cells.

Naturally most of this is based on animal trials, but it has to be said that the signs are generally positive and wit more human tests, studies and trials, I would expect to see this starting to appear in a lot more supplements and even drug based medicines too.

Does Celatrus Paniculatis Cause Any Side Effects?

With the distinct lack of human testing, its hard to be sure about this fact, but so far, there have been no reports of any adverse side effects occurring in the animals used in studies. Even when rats were given 5g per kg of body weight they experienced no ill effects.

Based on these facts, it certainly appears that its safe to take.

My Thoughts On Celastrus Paniculatis

With no real solid advice on daily doses,the lack of real human based studies, and despite the general feeling that its safe,  I still would not currently recommend taking Celastrus Paniculatus at the minute. 

It can be found in a couple of nootropic supplements currently at a dose of 60mg per serving and it has to be said that it doesn’t not appear to cause any issues or side effects.

Its just that the lack of human studies just troubles me somewhat, I have no problem trying new ingredients, but do like to think that there has been some human testing carried out beforehand.

Not For Me At The Minute – Maybe When Its Been Tested On Humans.

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The information in this website is for advice and guidance only. It is based on my own intensive research into nootropics and my personal experiences with certain products. It is not intended to replace professional medical advice, or to diagnose or treat any health conditions. All rights reserved.