Phosphatidylserine (PS): The Natural Brain Booster

Phosphatidylserine (PS): The Natural Brain Booster

It might be surprising to find out, but your brain has a natural capacity to increase its own brain power. In fact this ability exists in virtually all of the billions of cells that are in our body.

This ability is down to a phospholipid that can be found in every membrane of every cell, and is called Phosphatidylserine.

It offers a lot of benefits to our body and brain – Lets find out more about it and its effects.

phosphatidylserine

What Is Phosphatidylserine

Phosphatidylserine is a protein that is produced in the neural tissue found in the brain and the nerve endings.

Made in the body naturally, it is also found in some parts of our diet. The body absorbs it really well, and it has the ability to cross the blood brain barrier, meaning that it can benefit our brain tissues too.

Studies have shown that Phosphatidylserine is excellent at maintaining the health of our neurons. 

It is fatty in its composition which makes it very soluble in the myelin, the sheaf that surrounds and protects the neurons. It also helps to boost the speed that the signals pass along the nerve cell, boosting thought processing speed.

This ability actually helps us to form and retain short term memories, its uses as a treatment has included the treatment of Alzheimers disease.

Another area where it is useful at treating is in children with ADHD (Attention Deficit Hyperactivity Disorder). 

The use of Phosphatidylserine has shown some good results in the reducing of the symptoms such as attention deficit and hyperactivity.

It is also proven to help reduce stress in patients, scientist have discovered that it doesn’t do this by the regular way of reducing heart rate of surpressing cortisol (the stress hormone) production.

It appears to me more to do with the very close interaction between brain tissues and the neurons.

How Does Phosphatidylserine Work?

uses of phosphatidylserine

Phosphatidylserine works by maintaining and repairing the integrity of the neurons in the brain. 

In cases of cognitive disease such as Alzheimers for instance, the bunches of neurons in the brain gradually degrade, in time they are unable to transfer signals which results in the loss of memory and other cognitive functions.

With its bailout to easily cross the blood brain barrier, the use of Phosphatidylserine will help reduce the decline of the neurons, strengthening their structure and retaining the ability to process thoughts and memories.

Moods are another area that are dependant on the neurotransmitters present. Another area where Phosphatidylserine helps is in the regulation of the number of neurotransmitters release, it is particularly linked to dopamine, a key neurotransmitter that is responsible for our feelings of happiness and even euphoria.

Safe Doses

IN the treatment of conditions like Alzheimers for instance, experts agree that a dose of between 300-400mg Phosphatidylserine spread through the day is recommended.

Smaller doses ranging between 100mg – 200mg are generally accepted as what is required to help increase attention and focus. It is also thought to be quite effective at slowing down age related memory decline.

doses of phosphatidylserine

Does Phosphatidylserine Cause Any Side Effects?

As a naturally occurring compound, side effects are very unlikely, however, when supplementing with PS, you need to adhere to the recommended dosage, taking too much could cause:

  • Gas, and bloating
  • Insomnia
  • Stomach Upsets

During the early days of its use, PS was often taken from the cortex taken from brains of cattle, but this process was stopped due to the risk of passing on Creutzfeldt Jakob Disease – AKA Mad Cow Disease. 

Now days its largely sourced from plant sources, soy and sunflower being two popular choices.

Buying Phosphatidylserine

You can buy Phosphatidylserine as a stand alone product, but for best results I suggest that you take it as part of a stack – commonly found in top quality nootropic supplements.

One that I would suggest is Mind Lab Pro (Read My Full Review Here) made using a scientifically developed ingredient profile that includes PS taken from sunflowers. ( its thought to be better than soy based PS as some people are allergic to soy)

To Sum Up

If I had to choose just a handful of nootropic supplements to recommend, PS would be one of the first that I would pick. Its benefits and effects are well studied and documented and for me its one that you really should be taking in your nootropic stack.


The information in this website is for advice and guidance only. It is based on my own intensive research into nootropics and my personal experiences with certain products. It is not intended to replace professional medical advice, or to diagnose or treat any health conditions. All rights reserved.